ANTIGENS
ANTIGENS AND IMMUNOGENICITY
Question
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During the lag period between antigen contact and detection of adaptive immunity,
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antigen is hidden from the immune system in macrophages
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innate immune effectors are eliminating antigen
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innate immunity blocks the activation of adaptive immune effector cells
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new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
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Explanation:
Detailed explanation-1: -The adaptive, or acquired, immune response takes days or even weeks to become established-much longer than the innate response; however, adaptive immunity is more specific to an invading pathogen. Adaptive immunity is an immunity that occurs after exposure to an antigen either from a pathogen or a vaccination.
Detailed explanation-2: -The reaction can be divided into two stages – 1) Immediate, in which release of preformed mediators cause the immune response, and 2) Late-phase response 8-12 hours later, in which the cytokines released in the immediate stage stimulate basophils, eosinophils, and neutrophils even though the allergen is removed.
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