IMMUNOLOGY

ANTIGENS

ANTIGENS AND IMMUNOGENICITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
HLA-DR3 and HLA-DR4 is an example of what MHC/ Major Histocompatibility Complex?
A
Class I
B
Class II
C
Class III
D
Class IV
Explanation: 

Detailed explanation-1: -Major histocompatibility complex (MHC) class I and class II proteins play a pivotal role in the adaptive branch of the immune system. Both classes of proteins share the task of presenting peptides on the cell surface for recognition by T cells.

Detailed explanation-2: -The MHC is central to the adaptive immune response. The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and-DP, each being highly polymorphic.

Detailed explanation-3: -MHC Class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. These cells are important in initiating immune responses.

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