IMMUNOLOGY

Detailed explanation-1: -What Is an Immunogen? An immunogen is an antigen used to generate antibodies. Consequently, immunogen design is one of the most important aspects of antibody production: if the immunogen is poorly designed, the purified antibodies will be non-specific or have a low titer.

Detailed explanation-2: -The ability of structure-based design to control the shape and reactivity-the atomic-level chemistry-of an immunogen argues for it being one of the “most powerful” immunogen-design strategies. But antigenic reactivity is only one of the properties required to induce a protective immune response.