IMMUNOLOGY

Detailed explanation-1: -The five primary classes of immunoglobulins are IgG, IgM, IgA, IgD, and IgE. These are distinguished by the type of heavy chain found in the molecule. IgG molecules have heavy chains known as gamma-chains; IgMs have mu-chains; IgAs have alpha-chains; IgEs have epsilon-chains; and IgDs have delta-chains.

Detailed explanation-2: -Immunoglobulins are generally present either on the surface of B-cells or circulating freely in body fluids. The binding of the antibody to its specific antigen results in the formation of an antibody-antigen complex which elicits an immune response.

Detailed explanation-3: -IgA is the major antibody in secretions found in saliva, tears, colostrum, intestinal, genital tract, and respiratory secretions. IgE is a monomer. It has a molecular weight of 188 Kd and a serum concentration of 0.00005 mg/mL.