IMMUNOLOGY

ANTIGENS

ANTIGENS AND IMMUNOGENICITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following categories should be considered for foreigness of an immunogen?
A
Structure
B
Taxonomy
C
Shape
D
Weight
Explanation: 

Detailed explanation-1: -Two fundamental requirements must be met by a molecule to be immunogenic: (1) it should be foreign to activate the defense mechanism and (2) it must be of a certain complexity to react with the different components of the immune system necessary to induce the immune response.

Detailed explanation-2: -Foreignness-The immunogen must be foreign to the host. Immune responses take place only to substances that are not normally present in the body or normally exposed to the cells of the specific immune system. Under normal conditions, the immune system will discriminate between “self” and “non-self".

Detailed explanation-3: -Foreignness of the Immunogen (relative degree of difference of the immunogen from self-structures of the host): Chemical Composition: Molecular Size: Chemical Complexity: Dose of Immunogen: Genetic Constitution of the Host:

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