ANTIGENS
ANTIGENS AND IMMUNOGENICITY
Question
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Which of the following is incorrect with regard to antigen epitopes?
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An epitope may be shared by two different antigens
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protein molecule usually contains multiple epitopes
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B cells bind only processed antigen epitopes
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Epitopes may be linear or assembled
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Explanation:
Detailed explanation-1: -An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell. Binding between the receptor and epitope occurs only if their structures are complementary.
Detailed explanation-2: -The features of B cell epitope are hydrophilicity, surface accessibility, beta turns, exposed surface, polarity and antigenic properties of amino acids. These properties of polypeptides chains have been correlated with the location of the continuous and discontinuous conformational epitopes.
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