IMMUNOLOGY

ANTIGENS

T LYMPHOCYTES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What do CD8+ cells do?
A
migrate to the site of infection and target cells infected with intracellular organisms
B
coordinate immune responses to specific threats
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Memory CD8 T cells mediate rapid clearance of pathogens upon secondary infection owing to their elevated frequency, ready localization to peripheral sites of infection and their ability to rapidly expand and mount effector functions.

Detailed explanation-2: -Once activated by pAPCs, effector CD8 T cells can recognize any infected cell expressing MHC I loaded with its cognate peptide. This results in the killing of the infected cell and/or the production of antiviral cytokines both being important to control or clear viral infections.

Detailed explanation-3: -The most common form of CD8 is composed of a CD8- and CD8- chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail.

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