ANTIGENS
T LYMPHOCYTES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is antigen presentation?
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antigen fragments, cell peptides or epitope sequences that are loaded onto class I and class II MHC
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antigen fragments, cell peptides or epitope sequences that are loaded onto ONLY class I MHC
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antigen fragments, cell peptides or epitope sequences that are loaded onto ONLY class II MHC
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None of the above
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Explanation:
Detailed explanation-1: -Antigenic fragments and self-peptides are loaded onto MHC class II molecules in late endosomes or MHC class II containing compartments (MIICs).
Detailed explanation-2: -The two subunits form a peptide binding site and two ATP binding sites that face the cytosol. TAP binds peptides on the cytoplasmic side and translocates them under ATP consumption into the lumen of the ER. The MHC class I molecule is then, in turn, loaded with peptides in the lumen of the ER.
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