HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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first generation
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second generation
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Either A or B
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None of the above
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Detailed explanation-1: -Acrivastine (ak” ri vas’ teen) is a second generation antihistamine (H1 receptor blocker) that is used to treat allergic symptoms associated with hay fever, seasonal allergies, urticaria, angioedema and atopic dermatitis.
Detailed explanation-2: -First-generation antihistamines are primarily over-the-counter OTC) and are included in many combination products for cough, colds, and allergies. These include brompheniramine, chlorpheniramine (Chlor-Trimeton), and diphenhydramine (Benadryl).
Detailed explanation-3: -First-generation antihistamines block both histaminic and muscarinic receptors as well as passing the blood-brain barrier. Second-generation antihistamines mainly block histaminic receptors and do not pass the blood-brain barrier.