HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Select the examples for Type 2 Cytotoxic hypersensitivity .
|
|
Polyarteritis nodosa
|
|
|
Autoimmune haemolytic disease
|
|
|
Red blood cell lysis
|
|
|
White blood cells lysis in SLE
|
Explanation:
Detailed explanation-1: -Examples of Type II hypersensitivity reactions include blood transfusion reactions, erythroblastosis fetalis, and autoimmune hemolytic anemia.
Detailed explanation-2: -Blood transfusion reaction: ABO blood transfusion reaction is an example of type II hypersensitivity reaction. Human RBCs contains A and/or B antigen as major antigen on the surface of RBC. Other minor antigens such as Rh, Kell, Duffy etc are also present.
Detailed explanation-3: -Type II hypersensitivity reaction refers to an antibody-mediated immune reaction in which antibodies (IgG or IgM) are directed against cellular or extracellular matrix antigens, resulting in cellular destruction, functional loss, or tissue damage.
There is 1 question to complete.