IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are the typical manifestations of a type I hypersensitivity?
A
Induce systemic anaphylaxis and localized anaphylaxis such as hay fever, asthma, hives, food allergies, and eczema
B
includes blood transfusion reactions, erythroblastosis, fettles, and autoimmune hemolytic anemia
C
includes localized Arthus reaction and generalized reactions such as serum sickness, necrotizing vasculitis, glomerulonephritis, RA, and systemic lupus erythematosus
D
includes contact dermatitis, tubular lesions, and graft rejection
Explanation: 

Detailed explanation-1: -Clinical signs of type I hypersensitivity responses that occur after vaccine administration include facial or periorbital edema, urticaria, cutaneous hyperemia, generalized pruritus, salivation, hypotensive shock, tachypnea, vomiting, diarrhea, collapse, and even death (Figure 12-3).

Detailed explanation-2: -Patients may report skin itching, localized or diffuse pruritus, dizziness, faintness, and diaphoresis. Difficulty breathing can result from angioedema of the pharyngeal tissue, from bronchoconstriction, or from both. Patients may also report GI symptoms, including nausea, vomiting, diarrhea, and abdominal cramping.

Detailed explanation-3: -feeling lightheaded or faint. breathing difficulties – such as fast, shallow breathing. wheezing. a fast heartbeat. clammy skin. confusion and anxiety. collapsing or losing consciousness.

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