IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is used to explain why countries with improved hygiene are experiencing increases in asthma and allergy rates?
A
the hygiene hypothesis, which says that exposure to some pathogens early in life allows for a better T-cell balance
B
cleaner countries tend to have more air pollution
C
because hygiene is better, pathogens have become stronger
D
None of the above
Explanation: 

Detailed explanation-1: -The hygiene hypothesis proposes that childhood exposure to germs and certain infections helps the immune system develop. This teaches the body to differentiate harmless substances from the harmful substances that trigger asthma. In theory, exposure to certain germs teaches the immune system not to overreact.

Detailed explanation-2: -The hygiene hypothesis proposes that the stimulation of the immune system by microbes protects from the development of inflammatory diseases; therefore a reduced exposure to infectious agents may explain the rise in allergic and autoimmune diseases in industrialized countries (Yazdanbakhsh and Matricardi, 2004).

Detailed explanation-3: -The hygiene hypothesis is a hypothesis that suggests that the increased incidence of allergic and autoimmune disorders are linked to the tremendous changes in sanitation standards and practices that occurred in industrializing countries throughout the industrial revolution of the 19th and 20th centuries.

There is 1 question to complete.