IMMUNOLOGY

HYPERSENSITIVITY

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which immunoglobulin is responsible for type I hypersensitivity?
A
IgE
B
IgG
C
IgA
D
IgM
Explanation: 

Detailed explanation-1: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen.

Detailed explanation-2: -Type I reactions (i.e., immediate hypersensitivity reactions) involve immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils. Examples include anaphylaxis and allergic rhinoconjunctivitis.

Detailed explanation-3: -Immunoglobulin E(IgE), named in 1968, is the last of the five human immunoglobulins to be discovered and is typically associated with the diverse manifestations of allergic diseases.

There is 1 question to complete.