HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which immunoglobulin is responsible for type I hypersensitivity?
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IgE
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IgG
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IgA
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IgM
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Explanation:
Detailed explanation-1: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen.
Detailed explanation-2: -Type I reactions (i.e., immediate hypersensitivity reactions) involve immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils. Examples include anaphylaxis and allergic rhinoconjunctivitis.
Detailed explanation-3: -Immunoglobulin E(IgE), named in 1968, is the last of the five human immunoglobulins to be discovered and is typically associated with the diverse manifestations of allergic diseases.
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