HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following cytokines is NOT generally associated with allergic reactions?
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TNF-
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GM-CSF
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IL-4
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TGF-
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all of the answers are associated with allergic reactions
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Explanation:
Detailed explanation-1: -Type I: reaction mediated by IgE antibodies. Type II: cytotoxic reaction mediated by IgG or IgM antibodies. Type III: reaction mediated by immune complexes. Type IV: delayed reaction mediated by cellular response.
Detailed explanation-2: -So, the correct answer is ‘IgG and mast cells’.
Detailed explanation-3: -Upon exposure of the immune system to specific allergens, TH2 cells release high amounts of cytokines, mainly IL-4 and IL-13.
There is 1 question to complete.