IMMUNOLOGY

Detailed explanation-1: -Due to their potent biological activities, leukotrienes are considered to be chemical mediators in a number of inflammatory and allergic disorders, such as rheumatoid arthritis, inflammatory bowel disease, and bronchial asthma.

Detailed explanation-2: -Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease. Examples include montelukast, zafirlukast and zileuton.

Detailed explanation-3: -Included among these mediators are arachidonic acid derivatives (leukotrienes and prostaglandins), vasoactive peptides (kinins), phospholipid mediators (platelet activating factor), and cytokines (interleukins and other bioresponse modifiers).