HYPERSENSITIVITY
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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systemic anaphylaxis
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localized reaction
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food allergy
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None of the above
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Detailed explanation-1: -Type II hypersensitivity reaction refers to an antibody-mediated immune reaction in which antibodies (IgG or IgM) are directed against cellular or extracellular matrix antigens, resulting in cellular destruction, functional loss, or damage to tissues. Damage can occur through multiple mechanisms.
Detailed explanation-2: -Type I hypersensitivities include atopic diseases, which are an exaggerated IgE mediated immune responses (i.e., allergic: asthma, rhinitis, conjunctivitis, and dermatitis), and allergic diseases, which are immune responses to foreign allergens (i.e., anaphylaxis, urticaria, angioedema, food, and drug allergies).
Detailed explanation-3: -Type I reactions (i.e., immediate hypersensitivity reactions) involve immunoglobulin E (IgE)–mediated release of histamine and other mediators from mast cells and basophils. Examples include anaphylaxis and allergic rhinoconjunctivitis.