IMMUNOLOGY

HYPERSENSITIVITY

CYTOKINES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is a function of C-reactive protein (CRP) as an acute phase reactant?
A
Removes iron from gut
B
Modifies cholesterol metabolism
C
Promotes the activation of Complement
D
Modulates wound healing response
Explanation: 

Detailed explanation-1: -CRP binds to apoptotic cells, inhibits the assembly of terminal complement components, and promotes the opsonization of apoptotic cells (89, 90).

Detailed explanation-2: -CRP binds to phosphorylcholine on microbes. It is thought to assist incomplete binding to foreign and damaged cells and a cell enhances phagocytosis by macrophages, which express a receptor for CRP. It is also believed to play an important role in innate immunity, as an early defense system against infections.

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