IMMUNOLOGY

HYPERSENSITIVITY

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The process where each lymphocyte has a different receptor for a particular antigen, and is able to proliferate, creating clones of the initial lymphocyte with the specic receptor for the antigen.
A
colonial selection
B
clonal selection
C
humoral immunity
D
cell-mediated immunity
Explanation: 

Detailed explanation-1: -Clonal selection is the theory that specific antigen receptors exist on lymphocytes before they are presented with an antigen due to random mutations during initial maturation and proliferation. After antigen presentation, selected lymphocytes undergo clonal expansion because they have the needed antigen receptor.

Detailed explanation-2: -Clonal expansion of lymphocytes is a hallmark of vertebrate adaptive immunity. A small number of precursor cells that recognize a specific antigen proliferate into expanded clones, differentiate and acquire various effector and memory phenotypes, which promote effective immune responses.

Detailed explanation-3: -Antibodies are produced by B-lymphocytes after differentiation of B-lymphocytes into plasma cells. Polyclonal antibodies (PoAbs) can be raised by immunizing animals against the antigen of choice. PoAbs have various applications of analytical, diagnostic, and therapeutic significance.

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