IMMUNOLOGY

Detailed explanation-1: -The bacteria that causes tetanus makes a harmful protein, called a toxin. The name of the tetanus toxin is tetanospasmin. People who develop an immune response to this toxin are protected against tetanus. The tetanus vaccine is made by taking the tetanus toxin and inactivating it with a chemical.

Detailed explanation-2: -Toxoid vaccines contain a toxin or chemical made by the bacteria or virus. They make you immune to the harmful effects of the infection, instead of to the infection itself. Examples are the diphtheria and tetanus vaccines.

Detailed explanation-3: -Vaccines give you immunity to a disease without you getting sick first. They are made using killed or weakened versions of the disease-causing germ or parts of the germ (called antigens). For some vaccines, genetic engineering is used to make the antigens used in the vaccine.

Detailed explanation-4: -C. tetani produces two exotoxins, tetanolysin and tetanospasmin. Tetanospasmin is a neurotoxin and causes the clinical manifestations of tetanus.