IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ICAM-1 always binds with?
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LFA-1
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CD28
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CD 80/86
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IL-1
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Explanation:
Detailed explanation-1: -The LFA-1/ICAM-1 interaction plays a role in the firm adhesion of T cells to the endothelium, followed by transmigration of T cells across endothelial cells via intracellular signals that lead to cytoskeletal changes necessary for cell movement.
Detailed explanation-2: -ICAM-1 expression is highly induced by a variety of inflammatory cytokines; however, a degree of specificity among different cell types has been observed.
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