IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Ig G
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Ig E
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Ig M
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Ig A
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Detailed explanation-1: -Maternal immunoglobulin G (IgG) is transported across the placenta by an active, neonatal Fc receptor (FcRn) mediated process during pregnancy. This transport can confer short-term passive immunity1, 2, 3 and protect infants against infections during their first months of life.
Detailed explanation-2: -Abstract. THE IgG of the neonatal human infant is almost entirely derived by selective transplacental passage of maternal IgG, but IgA and IgM are considered incapable of transplacental passage.
Detailed explanation-3: -The efficiency of transplacental transfer of the different IgG subclasses was determined. Transfer of IgG1 and IgG4 was found to be significantly more efficient than that of IgG3 and IgG2. IgG2 was the subclass least efficiently transferred from mother to fetus.