IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which Immunoglobin has the highest concentration in serum?
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Ig G
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Ig M
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Ig A
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Ig D
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Explanation:
Detailed explanation-1: -IgG is synthesized mostly in the secondary immune response to pathogens. IgG can activate the classical pathway of the complement system, and it also is highly protective. The four subclasses of IgG include IgG1, IgG2, IgG3, and IgG4. IgG1 is around 65% of the total IgG.
Detailed explanation-2: -According to different references the normal concentrations of serum IgG and IgM are reported to be 560–1800 mg/dL (5.6–18 g/L) and 39–283 mg/dL (0.39–2.83/L), respectively [23], [24].
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