IMMUNE RESPONSE
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Ig M
|
|
|
Ig A
|
|
|
Ig G
|
|
|
Ig D
|
Detailed explanation-1: -IgA is the most abundant antibody isotype in mucosal secretions and owes its success in frontline immunity to its ability to undergo transcytosis across epithelial cells.
Detailed explanation-2: -The immunoglobulin A (IgA) is the predominant antibody isotype in the mucosal immune system, which widely exists in the gastrointestinal tract, respiratory tract, vaginal tract, tears, saliva, and colostrum. Normally, serum IgA shows a monomeric structure, while the mucosal IgA shows polymeric.
Detailed explanation-3: -Immunoglobulin A (Ig A, also referred to as sIgA in its secretory form) is an antibody that plays a role in the immune function of mucous membranes. The amount of IgA produced in association with mucosal membranes is greater than all other types of antibody combined.