IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Function of C1INH
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Prevents attachment of C5b67 complex to cell membranes
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Dissociates C1r and C1s from C1q
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Cofactor with I to inactivate C3b
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Acts as a cofactor with I to inactivate C4b
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Explanation:
Detailed explanation-1: -Complement 1 inhibitor (C1-INH)* is a critically important protein that controls activation of multiple plasma mediator pathways (1). This protein, a member of the serine protease inhibitor (serpin) group, originally was described as an inhibitor of C1 (2).
Detailed explanation-2: -C1 esterase inhibitor (C1-INH) is a multispecific protease inhibitor that is present in normal human plasma and serum and regulates enzymes of the complement, coagulation, fibrinolytic, and kinin-forming systems.
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