IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Function of Vitronectin
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Prevents attachment of C5b67 complex to cell membranes
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Dissociates C1r and C1s from C1q
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Cofactor with I to inactivate C3b
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Acts as a cofactor with I to inactivate C4b
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Explanation:
Detailed explanation-1: -The complement membrane attack complex (MAC) is classically known as a cytolytic effector of innate and adaptive immunity that forms pores in the plasma membrane of pathogens or targeted cells, leading to osmolysis.
Detailed explanation-2: -The membrane attack complex (MAC) punches a hole through the plasma membrane of the target cell, killing the pathogen. Found in Membrane Attack complex in Wikipedia. A rare but interesting human disease is associated with a malfunction of the MAC.
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