IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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 Question 
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 If activation of the complement system was to proceed uncontrolled, tissue damage and life-threatening systemic effects might result. Therefore, several proteins act as regulators to keep the reaction localized and ensure that infectious agents and not self-antigens are destroyed. 
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  First statement is true; Second statement is false 
 
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  First statement is false; Second statement is true 
 
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  Both statements are true 
 
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  Both statements are false 
 
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 Explanation: 
Detailed explanation-1: -The role of complement in various inflammatory disorders is multifaceted; for example, the activation of complement can significantly contribute to inflammation-mediated tissue damage, whereas inherited or acquired complement deficiencies highly favor the development of autoimmunity.
Detailed explanation-2: -2. The complement activation pathway that is triggered by the binding of an acute-phase protein to a pathogen is classical.
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