IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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If ATP is high in the cell, phosophofructokinase will be
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stimulated
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inhibited
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unaffected
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None of the above
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Explanation:
Detailed explanation-1: -PFK is able to regulate glycolysis through allosteric inhibition, and in this way, the cell can increase or decrease the rate of glycolysis in response to the cell’s energy requirements. For example, a high ratio of ATP to ADP will inhibit PFK and glycolysis.
Detailed explanation-2: -2. Low concentrations of ATP inhibited phosphofructokinase activity by decreasing the affinity of the enzyme for the other substrate, fructose 6-phosphate. Citrate, and other intermediates of the tricarboxylic acid cycle, also inhibited the activity of phosphofructokinase.
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