IMMUNOLOGY

IMMUNOGLOBULINS

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Most of the proteins of the complement system are inactive enzyme precursors, or zymogens, that are converted to active enzymes in a very precise order. One such means of activation is the classical pathway, which is triggered by antigen-antibody combination and involves eight of the proteins.
A
First statement is true; Second statement is false
B
First statement is false; Second statement is true
C
Both statements are true
D
Both statements are false
Explanation: 

Detailed explanation-1: -Complement is a system of plasma proteins that can be activated directly by pathogens or indirectly by pathogen-bound antibody, leading to a cascade of reactions that occurs on the surface of pathogens and generates active components with various effector functions.

Detailed explanation-2: -Complement operates in plasma, in tissues, or within cells (2). Complement proteins collaborate as a cascade to opsonize pathogens and induce a series of inflammatory responses helping immune cells to fight infection and maintain homeostasis.

There is 1 question to complete.