IMMUNOLOGY

IMMUNOGLOBULINS

CLASSICAL ALTERNATE AND LECTIN PATHWAYS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Polymerizes to cause cell lysis
A
C6
B
C7
C
C8
D
C9
Explanation: 

Detailed explanation-1: -CD59 prevents polymerization of C9 by the complex C5b–C6–C7–C8, thus preventing synthesis of MAC on normal cells.

Detailed explanation-2: -C9 self-polymerizes, leading to 12 to 18 C9 molecules that form a ring structure, completing the membrane attack complex.

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