IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Polymerizes to cause cell lysis
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C6
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C7
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C8
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C9
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Explanation:
Detailed explanation-1: -CD59 prevents polymerization of C9 by the complex C5b–C6–C7–C8, thus preventing synthesis of MAC on normal cells.
Detailed explanation-2: -C9 self-polymerizes, leading to 12 to 18 C9 molecules that form a ring structure, completing the membrane attack complex.
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