IMMUNOGLOBULINS
CLASSICAL ALTERNATE AND LECTIN PATHWAYS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The alternative pathway acts as a natural means of defense against infection; it is triggered not by antigen-antibody combination but by the presence of microorganisms.
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First statement is true; Second statement is false
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First statement is false; Second statement is true
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Both statements are true
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Both statements are false
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Explanation:
Detailed explanation-1: -This pathway is antibody-dependent. The alternative pathway seems to be of major importance in host defence against bacterial infection because, unlike the classical pathway, it is activated by invading micro-organisms and does not require antibody.
Detailed explanation-2: -The classical complement pathway typically requires antigen-antibody complexes for activation (specific immune response), whereas the alternative pathway can be activated by spontaneous complement component 3 (C3) hydrolysis, foreign material, pathogens, or damaged cells.
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