IMMUNOGLOBULINS
COMPLEMENT SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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In Class I MHC molecules, peptide-binding site consist of
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Explanation:
Detailed explanation-1: -The MHC class I heavy chain consists of three extracellular domains called 1, 2, and 3, a transmembrane domain, and a cytoplasmic domain. 2 microglobulin forms a fourth extracellular domain and is held in the complex by noncovalent interactions.
Detailed explanation-2: -Although similar to Class I, the MHC Class II molecule is composed of two membrane spanning proteins. Each chain is approximately 30 kilodaltons in size, and made of two globular domains as shown in the ribbon diagram. The domains are named Alpha-1 (blue-green), Alpha-2 (green), Beta-1 (purple) and Beta-2 (magenta).
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