IMMUNOLOGY

IMMUNOGLOBULINS

COMPLEMENT SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The initial complement component that is bound by complement-fixing antibodies is:
A
C1q
B
C1s
C
C3b
D
C9
Explanation: 

Detailed explanation-1: -Antibodies to C1q can be defined as immunoglobulins that bind to C1q via the antigen-binding region of the immunoglobulin molecules. Immunoglobulins, immunoglobulin aggregates, and immune complexes that bind to C1q via the Fc region of the immunoglobulin molecule should not be considered autoantibodies to C1q.

Detailed explanation-2: -complement fixation. noun. : the process of binding serum complement to the product formed by the union of an antibody and the antigen for which it is specific that occurs when complement is added to a mixture (in proper proportion) of such an antibody and antigen.

Detailed explanation-3: -COMPLEMENT FIXATION BY A TWO-COMPONENT ANTIBODY SYSTEM: IMMUNOGLOBULIN G AND IMMUNOGLOBULIN M ANTI-GLOBULIN (RHEUMATOID FACTOR)

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