IMMUNOLOGY

IMMUNOGLOBULINS

COMPLEMENT SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is NOT an important pro-inflammatory cytokine
A
IL-10
B
IL-1
C
TNF-a
D
IL-6
Explanation: 

Detailed explanation-1: -IL-10 is considered a potent antiinflammatory cytokine that strongly inhibits the production of proinflammatory cytokines. Recent studies have suggested that IL-10 also has immunostimulatory properties on CD4+, CD8+ T cells, and/or NK cells, resulting in increased IFN-gamma production.

Detailed explanation-2: -Proinflammatory cytokines are produced predominantly by activated macrophages and are involved in the up-regulation of inflammatory reactions. There is abundant evidence that certain pro-inflammatory cytokines such as IL-1, IL-6, and TNF- are involved in the process of pathological pain.

Detailed explanation-3: -Interleukin-4 and IL-10 are pleiotropic anti-inflammatory cytokines that function mainly by suppressing the pro-inflammatory milieu.

There is 1 question to complete.