IMMUNOLOGY

IMMUNOGLOBULINS

IMMUNOGLOBULIN STRUCTURE TYPES DISTRIBUTION BIOLOGICAL AND CHEMICAL PROPERTIES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
This antibody causes allergic reactions when attached to mast cells or basophils
A
IgG
B
IgM
C
IgE
D
IgA
Explanation: 

Detailed explanation-1: -IgE, mast cells, basophils, and eosinophils are essential components of allergic inflammation. Antigen-specific IgE production, with subsequent fixation of IgE to FcRI receptors on mast cells and basophils, is central to the initiation and propagation of immediate hypersensitivity reactions.

Detailed explanation-2: -Allergic reactions are the result of the production of specific IgE antibody to common, innocuous antigens. Allergens are small antigens that commonly provoke an IgE antibody response. Such antigens normally enter the body at very low doses by diffusion across mucosal surfaces and therefore trigger a TH2 response.

Detailed explanation-3: -Common allergic reactions, such as hay fever, certain types of asthma, and hives are linked to an antibody made by the body called immunoglobulin E (IgE). Each IgE antibody can be very specific. This means it reacts to certain pollens and other allergens.

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