IMMUNOLOGY

IMMUNOGLOBULINS

MONOCLONAL ANTIBODIES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why have monoclonal antibody cells been rejected by human tissues?
A
they are shaped oddly
B
viruses attack the cells
C
the human body creates its own antibodies in response to the antigens
D
the human body rejects the mouse cells
Explanation: 

Detailed explanation-1: -Anti-CD52 mAbs. A third class of mAbs, anti-CD52 mAbs, are used to prevent acute graft rejection.

Detailed explanation-2: -Abstract. Monoclonal antibodies are applied in various settings in renal transplantation. Depleting T-cell antibodies are used for treatment of steroid-resistant acute rejection and as induction therapy to reduce the intensity of concomitant immunosuppressive drug therapy.

Detailed explanation-3: -The role of MHC, therefore, is particularly important in organ transplantation, where non-self, normally allogeneic organs from one individual are transplanted into another individual. Antigen presentation by MHC can initiate various types of immunological rejection of transplants.

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