IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
All of these are specific treponemal tests except
A
FTA abs test
B
Trepsure
C
TPPA
D
RPR/VDRL
Explanation: 

Detailed explanation-1: -Venereal disease research laboratory (VDRL) test is a nontreponemal test, used for screening of syphilis due to its simplicity, sensitivity and low cost.

Detailed explanation-2: -Treponemal tests, also called confirmatory tests (FTA, TP-PA, EIA), detect antibodies specific to syphilis. Treponemal antibodies will appear earlier after acute infection than non-treponemal antibodies. The antibodies detected in these tests usually remain detectable for life even after successful treatment.

Detailed explanation-3: -Non-specific serological tests for syphilis The rapid plasma reagin (RPR) test, which has now largely superseded the earlier Venereal Disease Research Laboratory (VDRL) test, is a non-specific serological test for syphilis that uses cardiolipin as antigen.

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