IMMUNOLOGY

Detailed explanation-1: -Overview. Primary immunodeficiency disorders-also called primary immune disorders or primary immunodeficiency-weaken the immune system, allowing infections and other health problems to occur more easily.

Detailed explanation-2: -In cases of immune system overactivity, the body attacks and damages its own tissues (autoimmune diseases). Immune deficiency diseases decrease the body’s ability to fight invaders, causing vulnerability to infections.

Detailed explanation-3: -For children with immune dysregulation disorders, however, the immune system malfunctions, affecting multiple systems of the body. An overactive immune system attacks the body, causing dangerous inflammation and organ damage. An underactive immune system leaves the child vulnerable to infection.