IMMUNOLOGY

Detailed explanation-1: -Abstract. The biology of antigen presenting cells (APC) traditionally is studied in tissue culture systems using T cells that have been expanded beforehand by stimulation with antigen. Here we consider the distinctive roles of dendritic cells for sensitizing or priming T cells both in vitro and in vivo.

Detailed explanation-2: -Dendritic cells (DC) are a type of antigen-presenting cell (APC) that play an essential role in the adaptive immune system. The primary function of DCs is to present antigens and the cells are therefore sometimes referred to as “professional” APCs.

Detailed explanation-3: -Professional antigen presenting cells (APCs) are immune cells that specialize in presenting an antigen to a T-cell. The main types of professional APCs are dendritic cells (DC), macrophages, and B cells.

Detailed explanation-4: -Dendritic cells (DCs) Dendritic cells have the broadest range of antigen presentation and are necessary for activation of naive T cells. DCs present antigen to both helper and cytotoxic T cells.