MISCELLENOUS
VACCINATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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free antigen in a soluble form
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antigens presented with MHC I molecules
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haptens only
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antigens presented with MHC II molecules
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Detailed explanation-1: -The antigen is a peptide fragment generated by antigen-presenting cells when they degrade the foreign protein. To be recognized by a T cell, the antigen must bind a protein called the Major histocompatibility complex (MHC ). Cytotoxic T cells recognize antigen bound to MHC protein type 1.
Detailed explanation-2: -There are two types of MHC: MHC class I and MHC class II. MHC class I presents to cytotoxic T cells; MHC class II presents to helper T cells. The binding of the TCR to the MHC molecule containing the antigen peptide is a little unstable and so co-receptors are required.
Detailed explanation-3: -T-cell receptors recognize features both of the peptide antigen and of the MHC molecule to which it is bound.
Detailed explanation-4: - The antigens that TCRs bind are small peptide fragments, or epitopes, displayed by MHC molecules on the surface of cells.