IMMUNOLOGY

Detailed explanation-1: -Eosinophils are able to release granule content by piecemeal degranulation (PMD), classical exocytosis, compound exocytosis or cytolysis in response to various stimuli. Piecemeal degranulation describes the progressive and selective release of granule content mediated by transport vesicles.

Detailed explanation-2: -Eosinophil granules are remarkable rich repositories of a variety of receptors and contain secretory machinery that enables granules to selectively mobilize and secrete specific protein content intracellularly and to function as secretory organelles extracellularly after eosinophil lysis.