IMMUNOLOGY

Detailed explanation-1: -The smallpox vaccine, introduced by Edward Jenner in 1796, was the first successful vaccine to be developed. He observed that milkmaids who previously had caught cowpox did not catch smallpox and showed that inoculated vaccinia protected against inoculated variola virus.

Detailed explanation-2: -Two months later, in July 1796, Jenner took matter from a human smallpox sore and inoculated Phipps with it to test his resistance. Phipps remained in perfect health, the first person to be vaccinated against smallpox. Edward Jenner among patients in the Smallpox and Inoculation, coloured etching after J.

Detailed explanation-3: -In May 1796, Edward Jenner found a young dairymaid, Sarah Nelms, who had fresh cowpox lesions on her hands and arms (Figure 3). On May 14, 1796, using matter from Nelms’ lesions, he inoculated an 8-year-old boy, James Phipps.

Detailed explanation-4: -Edward Jenner, (17 May 1749-26 January 1823) was an English physician and scientist who was the pioneer of smallpox vaccine, the world’s first vaccine. Edward Jenner spent most of his life in Berkeley, Gloucestershire, where his father was the vicar.