IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The basic immunoglobulin (Ig) unit is composed of:
A
Two identical heavy and two identical light chains
B
Two identical heavy and two different light chains
C
Two different heavy and two identical light chains
D
Two different heavy and two different light chains
Explanation: 

Detailed explanation-1: -The Ig monomer is a “Y"-shaped molecule that consists of four polypeptide chains; two identical heavy chains and two identical light chains connected by disulfide bonds. Each chain is composed of structural domains called immunoglobulin domains.

Detailed explanation-2: -In higher vertebrates, there are two types of light chain – and – whereas heavy chains can be of five types: , , , and . The type of heavy chain defines the class of immunoglobulin: IgM, IgD, IgG, IgE and IgA, respectively.

Detailed explanation-3: -An Antibody Molecule Is Composed of Heavy and Light Chains The basic structural unit of an antibody molecule consists of four polypeptide chains, two identical light (L) chains (each containing about 220 amino acids) and two identical heavy (H) chains (each usually containing about 440 amino acids).

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