IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The first tenet of clonal selection theory relies SPECIFICALLY on ____
A
combinatorial joinings.
B
somatic mutations.
C
variations in the splicing process.
D
B-cell clones.
Explanation: 

Detailed explanation-1: -In 1958, Gustav Nossal and Joshua Lederberg showed that one B cell always produces only one antibody, which was the first direct evidence supporting the clonal selection theory.

Detailed explanation-2: -…developed a model, called the clonal selection theory of antibody formation, that explains how the body is able to recognize and respond to a virtually limitless number of foreign antigens. The theory states that an antigen entering the body does not induce the formation of an antibody specific to itself-as…

Detailed explanation-3: -When an antigen encounters the immune system, its epitopes eventually will react only with B-lymphocytes with B-cell receptors on their surface that more or less fit and this activates those B-lymphocytes. This process is known as clonal selection.

There is 1 question to complete.