MISCELLENOUS
VACCINATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the two antigens are immunologically unrelated.
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the two antigens are partially identical.
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the two antigens are immunologically identical.
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None of these
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Detailed explanation-1: -Nonidentity: It occurs when two antigens are unrelated (i.e. share no common epitopes). The antiserum forms an independent precipitin line with each antigen, and the two lines cross. 3. Partial identity: It occurs when two antigens share some epitopes but one or the other has a unique epitope (s).
Detailed explanation-2: -Three patterns of precipitin lines are visible in Ouchterlony Double Diffusion Pattern (Antigen Antibody Pattern). It is possible to see a pattern X, or pattern of identity, between antigens and antiserum. This indicates that antigens are immunologically similar.
Detailed explanation-3: -In the Ouchterlony assay, a series of samples (the antigens) are placed in the outer wells of a gel plate, and antibodies (antiserum) are placed in the center well, after which they diffuse out and form different geometric precipitation lines in the gel (Fig. 1).