MISCELLENOUS
VACCINATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Upon inhalation, a small dust particle reaches the alveolus. Which of the following innate immune mechanism gets activated?
|
|
the released granular contents of your granulocytes.
|
|
|
the physical barrier produced by hairs.
|
|
|
phagocytosis by macrophages.
|
|
|
mucus combined with the movement of cilia of the lining cells.
|
Explanation:
Detailed explanation-1: -By secretion of oxygen metabolites, lysozyme, antimicrobial peptides and proteases, and through processes of phagocytosis and intracellular killing, alveolar macrophages can eliminate the small inocula of typical microbes which are aspirated daily in the normal host (1).
Detailed explanation-2: -The NADPH oxidase complex is a key macrophage defensive response mechanism that delivers a regulated burst of ROS to phagosomal pathogens. This mechanism offers protection against Mycobacterium and Salmonella infection, among others (99, 100).
There is 1 question to complete.