IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Virulence factors are
A
molecules produced by pathogens that enable them to evade the host’s immune response
B
molecules produced by pathogens that enable them to attach to the host cells
C
molecules produced by pathogens that enable them to attach to the host cells
D
All of the above
Explanation: 

Detailed explanation-1: -Adherence and Colonization Factors. To cause infection, many bacteria must first adhere to a mucosal surface. Invasion Factors. Capsules and Other Surface Components. Endotoxins. Structure of Endotoxin.

Detailed explanation-2: -Virulence is described as an ability of an organism to infect the host and cause a disease. Virulence factors are the molecules that assist the bacterium colonize the host at the cellular level. These factors are either secretory, membrane associated or cytosolic in nature.

Detailed explanation-3: -Toxins. A major category of virulence factors are bacterial toxins. These are divided into two groups: endotoxins and exotoxins.

Detailed explanation-4: -Virulence factors characterized as important for attachment and invasion in human infection are CPS, -hemolysin, C proteins, and pilus-like proteins. Experimental models of infection have demonstrated that antibodies to these surface structures are protective.

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