IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What immunoglobulin is involved in immediate allergic responses?
A
IgM
B
IgG
C
IgE
D
IgD
Explanation: 

Detailed explanation-1: -Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen.

Detailed explanation-2: -A type II hypersensitivity is said to occur when damage to the host tissues is caused by cellular lysis induced by the direct binding of antibody to cell surface antigens. While the antibodies involved in type I HS are of the IgE isotype, those involved in type II HS reactions are mainly of the IgM or IgG isotype.

Detailed explanation-3: -Allergic reactions are the result of the production of specific IgE antibody to common, innocuous antigens. Allergens are small antigens that commonly provoke an IgE antibody response.

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