IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which is the major immunoglobulin in terms of concentration
A
IgG
B
IgA
C
IgM
D
IgD
Explanation: 

Detailed explanation-1: -IgG1 is around 65% of the total IgG. IgG2 forms an important host defense against bacteria that are encapsulated. IgG is the only immunoglobulin that crosses the placenta as its Fc portion binds to the receptors present on the surface of the placenta, protecting the neonate from infectious diseases.

Detailed explanation-2: -Immunoglobulin G (IgG) accounts for 70% to 75% of the total immunoglobulins in plasma. Only 35% is found in the plasma space, and 65% is extravascular. IgG consists of two -heavy and two light chains, linked by disulfides.

Detailed explanation-3: -Normal Ranges Adult: IgG 6.0-16.0g/L. IgA 0.8-3.0g/L.

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