MISCELLENOUS
VACCINATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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C3a
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C3b
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C4b
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C5a
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Detailed explanation-1: -The answer is a. C3b. C3b is the central molecule of the complement cascade which is produced in all 3 pathways. It opsonizes bacteria and it may also combine with other complement components to produce C5 convertase.
Detailed explanation-2: -Examples of opsonins include IgG antibody-part of the immune response-and the C3b molecule of the complement system. Each has receptors for both foreign particle and host phagocyte.
Detailed explanation-3: -Once created by one of the 3 pathways, C3b binds to multiple sites on the cell surface of the pathogen. It then binds to receptors on the surface of the macrophage or neutrophil. C3b is best known for its opsonizing activity because when it coats the microbe, phagocytosis activity is increased.