IMMUNOLOGY

Detailed explanation-1: -Lysogenic cycle. The lysogenic cycle allows a phage to reproduce without killing its host. Some phages can only use the lytic cycle, but the phage we are following, lambda ( ), can switch between the two cycles.

Detailed explanation-2: -This process of viral release from the cells results in lysis of cells, and hence, it is termed the ‘lytic phase’. There are a few relevant human viruses that have another phase of replication, usually referred to as the ‘latent phase’ – in other words, the virus lays dormant in this latent phase of replication.

Detailed explanation-3: -While latency is considered a dormant state of the virus, recent studies identified lytic gene expression during latency (1–4). Latently infected individuals can asymptomatically shed progeny virus (5), questioning the quiescent state during latent infection.

Detailed explanation-4: -In the lysogenic cycle, the viral genome gets inserted into the host genome. Viruses which can perform both lytic and lysogenic cycles are called temperature viruses.